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Endocrine Abstracts

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ea0022p381 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

CYP24A1 haplotypes are associated with differentiated thyroid carcinoma

Penna-Martinez Marissa , Ramos-Lopez Elizabeth , Stern Julienne , Kahles Heinrich , Hinsch Nora , Hansmann Martin-Leo , Selkinski Ivan , Grunwald Frank , Vorlander Christian , Wahl Robert A , Bechstein Wolf O , Zeuzem Stefan , Holzer Katharina , Badenhoop Klaus

Background: Previously, we reported an association of vitamin D receptor (VDR) polymorphisms and differentiated thyroid cancer (DTC) risk. The aim of the present study was to investigate other vitamin D pathway genes such as CYP27B1, CYP2R1 and CYP24A1 which code for enzymes that, respectively, synthesize and degrade 1,25(OH)2D3 in patients with DTC and healthy controls (HC). Also its influence on 25(OH)D3 and 1,25(OH)2D3 ...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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